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Article

A systematic review of the prevalence of germline pathogenic variants in patients with pancreatic cancer.

Journal of gastroenterology - 1 Aug 2021

Astiazaran-Symonds Esteban, Goldstein Alisa M

Abstract excerpt

The genetics of pancreatic ductal adenocarcinoma (PDAC) is complex with patients reported to harbor germline pathogenic variants (PVs) in many different genes. PDAC patients with familial pancreatic cancer (FPC) are more likely to carry germline PVs but there is no consensus main gene involved in FPC. We performed a systematic review of publications from PubMed and Scopus reporting PVs in patients with FPC,...

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Share to Carcinoma, Pancreatic Ductal
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Identifiers

PMID: 34255164
DOI: 10.1007/s00535-021-01806-y
PMCID: PMC8475496

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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