Article
An Emerging Paradigm for Germline Testing in Pancreatic Ductal Adenocarcinoma and Immediate Implications for Clinical Practice: A Review.
JAMA oncology - 1 May 2020
Rainone Michael, Singh Isha, Salo-Mullen Erin E, Stadler Zsofia K, O'Reilly Eileen M
Abstract excerpt
Importance: Pancreatic ductal adenocarcinoma (PDAC) is a malignant neoplasm with a rising incidence and is a leading public health challenge. Pancreatic ductal adenocarcinoma has been well characterized genomically, with findings of therapeutic actionability that have substantive implications for clinical practice based on recent high-level evidence. Observations: Pathogenic germline alterations (PGAs) are...
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