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Genetic Alterations of Periampullary and Pancreatic Ductal Adenocarcinoma: An Overview

21 Feb 2018

Abstract excerpt

Pancreatic Ductal AdenoCarcinoma (PDAC) is one of the most lethal malignancies of all solid cancers. Precancerous lesions for PDAC include PanIN, IPMNs and MCNs. PDAC has a poor prognosis with a 5-year survival of approximately 6%. Whereas Periampulary AdenoCarcinoma (PAC) having four anatomic subtypes, pancreatic, Common Bile Duct (CBD), ampullary and duodenum shows relative better prognosis. The highest...

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PMID: 30258276
DOI: 10.2174/1389202919666180221160753

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