Article
Association of Primary Sclerosing Cholangitis With HLA-C*07:02 in a Japanese Population.
Liver international : official journal of the International Association for the Study of the Liver - 1 Nov 2025
Okamoto Tatsuya, Okajima Hideaki, Kadohisa Masashi, Yamamoto Miki, Uebayashi Elena Yukie, Okumura Shinya, Sakamoto Katsunori, Ito Takashi, Hatano Etsuro
Abstract excerpt
BACKGROUND AND AIMS: Primary sclerosing cholangitis (PSC) is a progressive, refractory liver disease often requiring liver transplantation (LT). The association between the disease onset and specific human leukocyte antigen (HLA) typing has been noted, but its relevance in the Japanese population is unknown. METHODS: The HLA 5 locus (HLA-A, B, C, DRB1 and DQB1) 4-digit genotyping results of 31 patients with...
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