Article
Genetic Contribution to the Pathogenesis of Primary Biliary Cholangitis.
Journal of immunology research - 1 Jan 2017
Joshita Satoru, Umemura Takeji, Tanaka Eiji, Ota Masao
Abstract excerpt
Formerly termed primary biliary cirrhosis, primary biliary cholangitis (PBC) is a chronic and progressive cholestatic liver disease characterized by the presence of antimitochondrial antibodies. Ursodeoxycholic acid (UDCA) therapy is the most effective and approved treatment for PBC and leads to a favorable outcome in the vast majority of cases. Although the etiology of PBC has not yet been elucidated, human...
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