Article
A systematic review of associations between functional MRI activity and polygenic risk for schizophrenia and bipolar disorder.
Brain imaging and behavior - 1 Jun 2019
Dezhina Zalina, Ranlund Siri, Kyriakopoulos Marinos, Williams Steve C R, Dima Danai
Abstract excerpt
Genetic factors account for up to 80% of the liability for schizophrenia (SCZ) and bipolar disorder (BD). Genome-wide association studies have successfully identified several genes associated with increased risk for both disorders. This has allowed researchers to model the aggregate effect of genes associated with disease status and create a polygenic risk score (PGRS) for each individual. The interest in imaging...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.