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Article

Altered DLPFC-Hippocampus Connectivity During Working Memory: Independent Replication and Disorder Specificity of a Putative Genetic Risk Phenotype for Schizophrenia.

Schizophrenia bulletin - 1 Sept 2017

Schneider Michael, Walter Henrik, Moessnang Carolin, Schäfer Axel, Erk Susanne, Mohnke Sebastian, Romund Lydia, Garbusow Maria, Dixson Luanna, Heinz Andreas, Romanczuk-Seiferth Nina, Meyer-Lindenberg Andreas, Tost Heike

Abstract excerpt

Altered connectivity of dorsolateral prefrontal cortex (DLPFC) and hippocampus during working memory is considered an intermediate phenotype for schizophrenia (SCZ), but the relevance for other mental disorders with shared genetic background remains unknown. Here we investigated its presence in unaffected first-degree relatives of patients with bipolar disorder (BD) or major depressive disorder (MDD)....

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Identifiers

PMID: 28207073
DOI: 10.1093/schbul/sbx001
PMCID: PMC5581908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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