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Lrp5 A241T High-Bone-Mass Mutation Enhances Implant Osseointegration: An Experimental Murine Study.

Oral diseases - 1 Feb 2026

Zhou Danhong, Wang Xueting, Zhang Hui, Jiang Qifeng, Zhang Qinmeng, Miao Xiaoyan, Wang Ying, Yang Guoli, Jiang Zhiwei

Abstract excerpt

OBJECTIVES: This study aimed to assess the effect of the low-density lipoprotein receptor-related protein 5 (Lrp5) A241T gain-of-function mutation, which induces a high-bone-mass phenotype, on implant osseointegration in a murine model. METHODS: Heterozygous Lrp5 A241T mutant (Lrp5A/+) and wild-type (WT) littermate male mice on a C57BL/6J background were used. Micro-computed tomography (micro-CT) was performed to...

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PMID: 41025443
DOI: 10.1111/odi.70102

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SLA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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