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Article

The LRP5 high-bone-mass mutation causes alveolar bone accrual with minor craniofacial alteration.

Journal of periodontal research - 1 Aug 2023

Turkkahraman Hakan, Flanagan Shannan, Zhu Tianli, Bellido Teresita M, Yuan Xue

Abstract excerpt

BACKGROUND AND OBJECTIVE: Mutations in low-density lipoprotein receptor-related protein 5 (LRP5) cause various bone diseases. Several mouse models were generated to study the role of LRP5 in bone development. But most of the studies were confined to the appendicular skeleton. The role of LRP5 in the axial skeleton, especially in the craniofacial skeleton, is largely unknown. The aim of this study was to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37128744
DOI: 10.1111/jre.13130
PMCID: PMC10330384

Genes

LRP5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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