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Article

Shared genetics between metabolic traits and sensorineural hearing loss: a large-scale genome-wide cross-trait analysis.

Molecular genetics and genomics : MGG - 31 Aug 2025

Wang Xiaoyu, Xia Xiaoxu, Qiu Ke, Shu Tao, Pang Wendu, Ren Jianjun, Zhao Yu

Abstract excerpt

Sensorineural hearing loss (SNHL) has been epidemiologically linked to metabolic traits, yet their shared genetic basis remains unclear. We performed the largest genome-wide association study (GWAS) meta-analysis for SNHL and analyzed GWAS data from 14 metabolic traits to assess genetic correlations and infer causal relationships. Significant genetic correlations were observed between SNHL and high triglyceride...

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Share to Cholesterol Ester Transfer Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hearing Loss, Sensorineural

Share to Lipid Metabolism

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Identifiers

PMID: 40886219
DOI: 10.1007/s00438-025-02281-3

Genes

CETP
TG
APOA5
APOB
BUD13
SOST
TRIOBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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