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Article

Conventional and Shared Genetic Association Analysis Between Diabetes Mellitus and Sensorineural Hearing Loss.

Human mutation - 1 Jan 2026

Wang Xiaoyu, Zhang Ziyan, Qiu Ke, Luo Yaxin, Yi Xiaowei, Pang Wendu, Jiang Dan, Ren Jianjun, Zhao Yu

Abstract excerpt

Purpose: This study aims to investigate the epidemiological and genetic associations between diabetes mellitus (DM) and sensorineural hearing loss (SNHL) across different subtypes. Methods: We analyzed 502,490 participants from the UK Biobank using multivariate logistic regression to examine the association between DM and SNHL, considering gender, age, and HbA1c levels. Genetic correlations and causality were...

Read the complete abstract on PubMed

Topics

Humans
Hearing Loss, Sensorineural
Female
Diabetes Mellitus, Type 2
Male
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Association Studies

Middle Aged

Polymorphism, Single Nucleotide

Genome-Wide Association Study

Linkage Disequilibrium

Aged

Source

Open in PubMed Open full text

Identifiers

PMID: 42746577
DOI: 10.1155/humu/5099141
PMCID: PMC13576905

Genes

ARHGEF28
TCF7L2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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