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Article

New insights into the complex genetic architecture of age-related hearing loss.

European journal of medical genetics - 1 Jul 2026

Bonnet Crystel, Aiche Salim, Boucher Sophie

Abstract excerpt

Age-related hearing loss (ARHL), or presbycusis, is a very common sensory disorder resulting from cumulative exposure to environmental factors, biological aging and a significant genetic component. Although most cases of ARHL result from the combined influence of numerous low-effect variants, the increasing number of monogenic forms has shown the importance of rare, highly penetrant mutations in ARHL. Advances in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42379497
DOI: 10.1016/j.ejmg.2026.105089

Genes

CDH23
EYA4
GRHL2
ILDR1
KCNQ4
MYO6
MYO7A
TECTA
TMC1
WFS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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