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Epigenetic Modulation and Bone Metastasis: Evolving Therapeutic Strategies

31 Jul 2025

Abstract excerpt

Bone metastasis remains a significant cause of morbidity and diminished quality of life in patients with advanced breast, prostate, and lung cancers. Emerging research highlights the pivotal role of reversible epigenetic alterations, including DNA methylation, histone modifications, chromatin remodeling complex dysregulation, and non-coding RNA networks, in orchestrating each phase of skeletal colonization....

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PMID: 40872531
DOI: 10.3390/ph18081140

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