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Article

The genetic architecture of bone metastases: unveiling the role of epigenetic and genetic modifications in drug resistance

22 Apr 2025

Abstract excerpt

Bone metastases represent frequent and severe complications in various cancers, notably impacting prognosis and quality of life. This review article delves into the genetic and epigenetic mechanisms underpinning drug resistance in bone metastases, a key challenge in effective cancer treatment. The development of drug resistance in cancer can manifest as either intrinsic or acquired, with genetic heterogeneity...

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Identifiers

PMID: 40342734
DOI: 10.20517/cdr.2025.28

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