[Parkinson's Disease Associated with Mutations in the LRRK2 Gene: Approaches to Therapy].

doi:10.31857/S0026898425030024

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Article

[Parkinson's Disease Associated with Mutations in the LRRK2 Gene: Approaches to Therapy].

Molekuliarnaia biologiia - 1 Jan 2025

Usenko T S, Pchelina S N

Abstract excerpt

Leucine-rich repeat kinase 2 (LRRK2) belongs to the subfamily of tyrosine kinase-like kinases, the main function of which is to catalyze the transfer of γ-phosphate from ATP to the substrate in the cell due to the kinase domains. The exact functions of LRRK2 in the cell remain unknown. It has bee...

Topics

Humans
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
Parkinson Disease
Mutation
Protein Multimerization
Animals

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