Polygenic scores for depression are associated with indices of neighborhood adversity.

Abstract excerpt

Genome-wide association studies have allowed for the creation of polygenic scores (PGSs) reflecting genetic liability for depression, yet recent work suggests that these PGSs may also reflect greater genetic propensity toward higher levels of stress exposure. The current study sought to extend prior findings to examine whether an established depression PGS (DEP-PGS) is associated with greater stress exposure at...

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