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Article

Socioeconomic inequalities, genetic susceptibility, and risks of depression and anxiety: A large-observational study.

Journal of affective disorders - 15 Dec 2024

Qi Xin, Yang Jin, Liu Li, Hao Jingcan, Pan Chuyu, Wen Yan, Zhang Na, Wei Wenming, Kang Meijuan, Cheng Bolun, Cheng Shiqiang, Zhang Feng

Abstract excerpt

OBJECTIVES: This study aimed to investigate the interplay between genetic susceptibility and socioeconomic disparities on psychiatric disorders. METHODS: In this study, we utilized data from the UK Biobank to analyze the Generalized Anxiety Disorder (GAD)-7 scale (N = 74,425) and the Patient Health Questionnaire (PHQ)-9 (N = 74,101), along with the Index of Multiple Deprivation (IMD). The polygenic risk score...

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PMID: 39236878
DOI: 10.1016/j.jad.2024.09.009

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