Article

Polygenic scores for psychiatric traits mediate the impact of multigenerational history for depression on offspring psychopathology

2024-07-17

Abstract excerpt

<title>Abstract</title> <p>A family history of depression is a well-documented risk factor for offspring psychopathology. However, the genetic mechanisms underlying the intergenerational transmission of depression remain unclear. We used genetic, family history, and diagnostic data from 11,875 9–10 year-old children from the Adolescent Brain Cognitive Development study. We estimated and investigated the children’...

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Literature Corpus work: bfb1cb17-6e21-5906-afd5-c4faf6d7cb2b
DOI: 10.21203/rs.3.rs-4264742/v1

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