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Article

Oncogenic RBM19 modulated by MAX-mediated allelic transcription regulation in hepatocellular carcinoma progression.

Archives of biochemistry and biophysics - 1 Oct 2025

Zheng Yanxiu, Yin Xiaolei, Han Linyu, Liu Shuqing, Zhang Nasha, Yang Yanting, Yang Ming

Abstract excerpt

Hepatocellular carcinoma (HCC), the most common type of liver cancer, exhibits the highest incidence in Asia and Africa. However, the mechanisms underlying the malignant transformation of normal cells to HCC cells remain poorly understood. MYC-associated protein X (MAX) functions as an oncogenic transcription factor (TF) in HCC by binding to E-box elements in promoters or enhancers of target gene. Using our...

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Share to Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40774403
DOI: 10.1016/j.abb.2025.110576

Genes

RBM19
MAX
TF
C1QTNF6
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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