Article
Genome-wide functional integration identified MAZ-controlled RPS14 dysregulation in hepatocellular carcinoma.
Archives of toxicology - 1 Mar 2024
Han Linyu, Huo Yanfei, Huang Linying, Zheng Yanxiu, Yu Xinyuan, Zhang Nasha, Yang Ming
Abstract excerpt
Chronic infection with Hepatitis B virus (HBV) significantly increases the risk of hepatocellular carcinoma (HCC), particularly in Eastern Asia. However, only a subset of individuals with chronic HBV infection develop HCC, suggesting the role for genetic factors in HCC etiology. Despite genome-wide association studies (GWASs) identifying multiple single nucleotide polymorphisms (SNPs) associated with HBV-related...
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