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Article

UHRF1 Drives Hepatocellular Carcinoma Progression via Epigenetic Repression of SFMBT2

2025-12-04

Abstract excerpt

<title>Abstract</title> <p>Background Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality, necessitating the identification of novel therapeutic targets. UHRF1 is an epigenetic regulator implicated in various cancers, but its precise mechanistic role in HCC progression remains incompletely understood. This study investigates the epigenetic mechanisms by which UHRF1 promotes HCC pathogene...

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Literature Corpus work
945ff3e3-0929-5ac5-af77-f64c568b195f
DOI
10.21203/rs.3.rs-7981198/v1
Open publication

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