Article
ARID2: a new tumor suppressor gene in hepatocellular carcinoma.
Oncotarget - 1 Nov 2011
Zhao Hong, Wang Jian, Han Yongqing, Huang Zhen, Ying Jianming, Bi Xinyu, Zhao Jianjun, Fang Yi, Zhou Haitao, Zhou Jianguo, Li Zhiyu, Zhang Yefan, Yang Xue, Yan Tao, Wang Linfang, Torbenson Michael S, Cai Jianqiang
Abstract excerpt
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, however, genetic-environmental interactions and mechanisms associated with the development of HCC remains largely unclear. Our recent work described novel inactivating mutations of ARID2 (AT-rich interactive domain 2) in four major subtypes of HCC through exomic sequencing of ten HCV-associated HCCs and subsequent evaluation of the...
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