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Signal Activation of Hepatitis B Virus–Related Hepatocarcinogenesis by Up-regulation of SUV39h1

6 Jun 2020

Abstract excerpt

BACKGROUND: Hepatitis B virus (HBV) X (HBx) protein is associated with hepatocellular carcinogenesis via the induction of malignant transformation and mitochondrial dysfunction. However, the association between HBx and histone methyltransferase in carcinogenesis has not been fully clarified. In the current study, we analyzed the association between HBx and the histone methyltransferase suppressor of variegation...

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PMID: 32514521
DOI: 10.1093/infdis/jiaa317

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