Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polygenic risk of coronary artery disease for long-term survivors of breast cancer.

Journal of the National Cancer Institute - 1 Oct 2025

Watt Gordon P, Reiner Anne S, Shu Xiang, Malone Kathleen E, Knight Julia A, John Esther M, Chow Eric J, Lynch Charles F, Mellemkjær Lene, Woods Meghan, Liang Xiaolin, Tran Anh Phong, Oh Jung Hun, Derkach Andriy, Bernstein Jonine L

Abstract excerpt

BACKGROUND: Cardiovascular disease is a leading cause of death for long-term breast cancer survivors. We evaluated whether a polygenic risk score for coronary artery disease (CAD-PRS) was associated with the risk of incident CAD for survivors of unilateral or contralateral breast cancer. METHODS: The study included 1307 women with breast cancer first diagnosed at younger than 55 years of age who participated in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anthracyclines
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cancer Survivors

Share to Coronary Artery Disease

Share to Follow-Up Studies

Share to Incidence

Share to Multifactorial Inheritance

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 40665521
DOI: 10.1093/jnci/djaf189
PMCID: PMC12505140

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polygenic risk of coronary artery disease for long-term survivors of breast cancer.PMID 40665521Read ↗

Genomic risk prediction of coronary artery disease in women with breast cancer: a prospective cohort study.Semantic proximity Read ↗

Broad Clinical Manifestations of Polygenic Risk for Coronary Artery Disease in the Women’s Health InitiativeSemantic proximity Read ↗

A Polygenic Risk Score for Coronary Artery Disease Improves the Prediction of Early-Onset Myocardial Infarction and Mortality in MenSemantic proximity Read ↗

Sex-specific survival bias and interaction modeling in coronary artery disease risk predictionSemantic proximity Read ↗

Dynamic Importance of Genomic and Clinical Risk for Coronary Artery Disease Over the Life CourseSemantic proximity Read ↗

Sex-Specific Survival Bias and Interaction Modeling in Coronary Artery Disease Risk PredictionSemantic proximity Read ↗

A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study.Semantic proximity Read ↗

Genome-Wide Polygenic Score, Clinical Risk Factors, and Long-Term Trajectories of Coronary Artery Disease.Semantic proximity Read ↗

An integrated germline and somatic genomic model for coronary artery disease.Semantic proximity Read ↗

Limitations of Contemporary Guidelines for Managing Patients at High Genetic Risk of Coronary Artery Disease.Semantic proximity Read ↗

Cardiovascular disease and breast cancer risk: a Multivariate Mendelian randomizationSemantic proximity Read ↗

An Integrated Germline and Somatic Genomic Model Improves Risk Prediction for Coronary Artery DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.