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Article

Sex-Specific Survival Bias and Interaction Modeling in Coronary Artery Disease Risk Prediction

29 Dec 2022

Abstract excerpt

BACKGROUND: The 10-year Atherosclerotic Cardiovascular Disease risk score is the standard approach to predict risk of incident cardiovascular events, and recently, addition of coronary artery disease (CAD) polygenic scores has been evaluated. Although age and sex strongly predict the risk of CAD, their interaction with genetic risk prediction has not been systematically examined. This study performed an extensive...

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PMID: 36580301
DOI: 10.1161/circgen.121.003542

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