Article
Hearing function and ossicular deformities and fractures in the oim mouse model of brittle bone disease.
Hearing research - 1 Sept 2025
Ugarteburu Maialen, Shaheen Aliah F, Rau Christoph, Cardoso Luis, Richter Claus-Peter, Carriero Alessandra
Abstract excerpt
Hearing loss is a prevalent symptom of osteogenesis imperfecta (OI), a group of collagen type I-related skeletal disorders, commonly known as brittle bone disease. Clinical manifestation of hearing loss in OI often presents with stapes footplate fixation and hypodense foci in the otic capsule. However, the etiology and evolution of OI-hearing loss and its relation to bone abnormalities are still unknown. This...
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