Article
Heterozygous oim mice exhibit a mild form of osteogenesis imperfecta.
Bone - 1 Dec 1996
Saban J, Zussman M A, Havey R, Patwardhan A G, Schneider G B, King D
Abstract excerpt
The oim strain of mice is one of several rodent models that exhibit an osteogenesis imperfecta (OI) phenotype. These mice have a mutation in the gene encoding alpha-2 chain of type I procollagen that prevents proper assembly of this propeptide with alpha-1 propeptides. Homozygous oim mice experie...
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