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Article

Ectopic Mineralization and Conductive Hearing Loss in Enpp1asj Mutant Mice, a New Model for Otitis Media and Tympanosclerosis.

PloS one - 1 Jan 2016

Tian Cong, Harris Belinda S, Johnson Kenneth R

Abstract excerpt

Otitis media (OM), inflammation of the middle ear, is a common cause of hearing loss in children and in patients with many different syndromic diseases. Studies of the human population and mouse models have revealed that OM is a multifactorial disease with many environmental and genetic contributing factors. Here, we report on otitis media-related hearing loss in asj (ages with stiffened joints) mutant mice,...

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Source

Open in PubMed Open full text

Identifiers

PMID: 27959908
DOI: 10.1371/journal.pone.0168159
PMCID: PMC5154548

Genes

ABR
ENPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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