Article
Comparison of bone tissue properties in mouse models with collagenous and non-collagenous genetic mutations using FTIRI.
Bone - 1 Nov 2012
Coleman Rhima M, Aguilera Laura, Quinones Layla, Lukashova Lyudamila, Poirier Christophe, Boskey Adele
Abstract excerpt
Understanding how the material properties of bone tissue from the various forms of osteogenesis imperfecta (OI) differ will allow us to tailor treatment regimens for affected patients. To this end, we characterized the bone structure and material properties of two mouse models of OI, the osteogenesis imperfecta mouse (oim/oim) and fragilitas ossium (fro/fro), in which bone fragility is due to a genetic defect in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
