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AdmixPower: Statistical Power and Sample Size Estimation for Mapping Genetic Loci in Admixed Populations.

Genetics - 1 Nov 2017

Gautam Yadu, Altaye Mekibib, Xie Changchun, Mersha Tesfaye B

Abstract excerpt

Admixed populations result from recent admixture of two or more ancestral populations with divergent allele frequencies. The genome of each admixed individual is a mosaic of haplotypes inherited from the ancestral populations. Despite the substantial work to assess power and sample size requirements for association mapping in genetically homogeneous populations of European ancestry, power and sample size...

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Identifiers

PMID: 28951529
DOI: 10.1534/genetics.117.300312
PMCID: PMC5676228

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