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Long term exposure to benzo[b]fluoranthene does not induce mutations in Mutamouse male germ cells.

Reproductive toxicology (Elmsford, N.Y.) - 1 Oct 2025

Stewart Madison T, Zhou Gu, LeBlanc Danielle P M, Dodge Annette E, Meier Matthew J, Williams Andrew, Long Alexandra S, White Paul A, Yauk Carole L, Marchetti Francesco

Abstract excerpt

Germ cell mutations can be inherited and lead to genetic disorders in the offspring. Thus, it is critical to identify environmental exposures that impact the germline. Polycyclic aromatic hydrocarbons (PAHs) are widespread combustion by-products found in food, tobacco smoke, and urban air. Benzo[b]fluoranthene (BbF) is a PAH that is classified as a possible human carcinogen. Studies using the transgenic mouse...

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Fluorenes
PAH gene
Germ-Line Mutation
Mice
Mice, Transgenic

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PMID: 40633786
DOI: 10.1016/j.reprotox.2025.108985

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PAH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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