Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NAT10-mediated acetylation of NIK mRNA in B cells promotes IgA production

4 Jul 2025

Abstract excerpt

Abstract The regulation of IgA expression is crucial for maintaining mucosal immune homeostasis, providing a vital defense mechanism against pathogens at mucosal surfaces. However, the intricate mechanisms governing IgA class-switch recombination and its dysregulation in diseases such as inflammatory bowel disease remain a significant challenge in the field. Our study delves into the significance of IgA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40615576
DOI: 10.1038/s44319-025-00509-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NAT10-mediated acetylation of NIK mRNA in B cells promotes IgA productionPMID 40615576Read ↗

Research progress on NAT10-mediated acetylation in normal development and diseaseSemantic proximity Read ↗

Targeting NAT10 suppresses T <sub>FH</sub> responses and alleviates allergic asthma via an ac4C-TOX2 axisSemantic proximity Read ↗

Autoacetylation of NAT10 is critical for its function in rRNA transcription activation.Semantic proximity Read ↗

NAT10‐mediated mRNA N4‐acetylcytidine modification promotes bladder cancer progressionSemantic proximity Read ↗

Nsun2 coupling with RoRγt shapes the fate of Th17 cells and promotes colitisSemantic proximity Read ↗

Lactylation of NAT10 promotes N4‐acetylcytidine modification on tRNASer-CGA-1-1 to boost oncogenic DNA virus KSHV reactivationSemantic proximity Read ↗

B-Cell Epigenetic Modulation of IgA Response by 5-Azacytidine and IgA NephropathySemantic proximity Read ↗

The nuclear role of methionine adenosyltransferase 2A in immunoglobulin class switch recombinationSemantic proximity Read ↗

An Altered Glycome Shapes IgA B-Cell Responses and Gut Immunity During Intestinal InflammationSemantic proximity Read ↗

Role of let-7b in the regulation of<i>N</i>-acetylgalactosaminyltransferase 2 in IgA nephropathySemantic proximity Read ↗

Critical roles of chemokine receptor CCR10 in regulating memory IgA responses in intestines.Semantic proximity Read ↗

Structure and function of human NXPE1, a sialic acid <i>O</i> -acetyltransferaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.