Hierarchical structural component model for pathway analysis of multinomial phenotypes.

Abstract excerpt

BACKGROUND: Many statistical methods for pathway analysis have been used to identify novel pathways from biomarkers associated with a certain disease. However, most of these methods are based on single pathway analysis and do not consider multiple pathways simultaneously. To address this issue, a hierarchical structural component model (HisCoM) was developed, which takes into account all pathways at the same...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biomarkers
• Share to Models, Statistical
• Share to Phenotype