Article
Identification of differential gene pathways with principal component analysis.
Bioinformatics (Oxford, England) - 1 Apr 2009
Ma Shuangge, Kosorok Michael R
Abstract excerpt
MOTIVATION: Development of high-throughput technology makes it possible to measure expressions of thousands of genes simultaneously. Genes have the inherent pathway structure, where pathways are composed of multiple genes with coordinated biological functions. It is of great interest to identify differential gene pathways that are associated with the variations of phenotypes. RESULTS: We propose the following...
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