Article
Kernel-based hierarchical structural component models for pathway analysis.
Bioinformatics (Oxford, England) - 26 May 2022
Hwangbo Suhyun, Lee Sungyoung, Lee Seungyeoun, Hwang Heungsun, Kim Inyoung, Park Taesung
Abstract excerpt
MOTIVATION: Pathway analyses have led to more insight into the underlying biological functions related to the phenotype of interest in various types of omics data. Pathway-based statistical approaches have been actively developed, but most of them do not consider correlations among pathways. Because it is well known that there are quite a few biomarkers that overlap between pathways, these approaches may provide...
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