Article

A systems approach to refine disease taxonomy by integrating phenotypic and molecular networks

2017-11-14

Abstract excerpt

<h4>Summary</h4> The International Classification of Diseases (ICD) relies on clinical features and lags behind the current understanding of the molecular specificity of disease pathobiology, necessitating approaches that incorporate growing biomedical data for classifying diseases to meet the needs of precision medicine. Our analysis revealed that the heterogeneous molecular diversity of disease chapters and the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3d140497-e20e-5cbc-bb61-50a59822ac4d
DOI: 10.1101/219089

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A systems approach to refine disease taxonomy by integrating phenotypic and molecular networksDOI 10.1101/219089Read

A Systems Approach to Refine Disease Taxonomy by Integrating Phenotypic and Molecular Networks.Semantic proximity Read

Disease classification: from phenotypic similarity to integrative genomics and beyond.Semantic proximity Read

A Multi-Dimensional Approach to Map Disease Relationships Challenges Classical Disease ViewsSemantic proximity Read

The multiplex network of human diseasesSemantic proximity Read

A Multi-Dimensional Approach to Map Disease Relationships Challenges Classical Disease Views.Semantic proximity Read

DiseaseConnect: a comprehensive web server for mechanism-based disease-disease connections.Semantic proximity Read

The expanded human disease network combining protein-protein interaction information.Semantic proximity Read

Decipher the connections between proteins and phenotypes.Semantic proximity Read

A Visual Phenotype-Based Differential Diagnosis Process for Rare Diseases.Semantic proximity Read

Network-based characterization of disease-disease relationships in terms of drugs and therapeutic targets.Semantic proximity Read

Integrated molecular, clinical, and ontological analysis identifies overlooked disease relationshipsSemantic proximity Read

Human symptoms-disease network.Semantic proximity Read