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The significance of mitochondrial DNA changes during the onset and progression of head and neck squamous cell carcinoma.

Future oncology (London, England) - 1 Jan 2026

Aminuddin Amnani, Wong Poh Kuan, Masre Siti Fathiah, Ng Pei Yuen, Zakaria Muhammad Asyaari, Chua Eng Wee

Abstract excerpt

Mitochondrial DNA (mtDNA) is integral to cellular function. Alterations in mtDNA can lead to significant disruptions in mitochondrial function, including cellular energy production, metabolism, and apoptosis regulation. Mitochondrial dysfunction has emerged as a crucial factor in the progression of cancer, including head and neck squamous cell carcinoma (HNSCC). Based on a literature search conducted from August...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Squamous Cell Carcinoma of Head and Neck

Source

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Identifiers

PMID: 40605739
DOI: 10.1080/14796694.2025.2521871
PMCID: PMC12802993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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