Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An ABCA1 missense variant decreases cholesterol efflux and confers Alzheimer's disease risk in the Chinese population.

Journal of Alzheimer's disease : JAD - 1 Aug 2025

Liu Sze Kei, Cao Han, Yang Xin, Zhou Xiaopu, Chen Yu, Fu Wing-Yu, Chan San Yuen, Ip Fanny Cf, Mok Kin Y, Mok Vincent Ct, Kwok Timothy Cy, Hardy John, Fu Amy Ky, Ip Nancy Y

Abstract excerpt

BackgroundGenetic studies have revealed that single-nucleotide polymorphisms (SNPs) of ABCA1 are associated with Alzheimer's disease (AD) risk. However, their AD-related effects in non-European populations are not well studied. Moreover, the functional implications of these AD-associated SNPs remain unclear.ObjectiveWe examined the AD associations of ABCA1 SNPs in the Chinese population and investigated the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to ATP Binding Cassette Transporter 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Cholesterol

Share to East Asian People

Share to Hong Kong

Share to Mutation, Missense

Source

Identifiers

PMID: 40598857
DOI: 10.1177/13872877251350722

Genes

ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An ABCA1 missense variant decreases cholesterol efflux and confers Alzheimer's disease risk in the Chinese population.PMID 40598857Read ↗

A novel intronic polymorphism of ABCA1 gene reveals risk for sporadic Alzheimer's disease in Chinese.Semantic proximity Read ↗

A survey of ABCA1 sequence variation confirms association with dementia.Semantic proximity Read ↗

Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism.Semantic proximity Read ↗

The ABC's of Alzheimer risk gene ABCA7.Semantic proximity Read ↗

The role of ABCA7 in Alzheimer’s disease: evidence from genomics, transcriptomics and methylomicsSemantic proximity Read ↗

The role of ATP-binding cassette subfamily A in the etiology of Alzheimer’s diseaseSemantic proximity Read ↗

Analyzing large-scale samples confirms the association between the ABCA7 rs3764650 polymorphism and Alzheimer's disease susceptibility.Semantic proximity Read ↗

ABCA1 activity is associated with reduced Alzheimer’s Disease risk in APOE ε4 non-carriersSemantic proximity Read ↗

ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease.Semantic proximity Read ↗

The polymorphism of the ATP-binding cassette transporter 1 gene modulates Alzheimer disease risk in Chinese Han ethnic population.Semantic proximity Read ↗

ABCA7 gene and the risk of Alzheimer's disease in Han Chinese in Taiwan.Semantic proximity Read ↗

Alzheimer's Disease and Effects of ABCA7 Polymorphisms: A Review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.