Article
ABCA7 gene and the risk of Alzheimer's disease in Han Chinese in Taiwan.
Neurobiology of aging - 1 Oct 2014
Liao Yi-Chu, Lee Wei-Ju, Hwang Jeng-Ping, Wang Yen-Feng, Tsai Chia-Fen, Wang Pei-Ning, Wang Shuu-Jiun, Fuh Jong-Ling
Abstract excerpt
The ATP-binding cassette, subfamily A, member 7 gene (ABCA7) was recently identified as a susceptible gene of Alzheimer's disease (AD) in the Caucasian population and African Americans. To test its genetic effect in the Han-Chinese population, 536 AD cases and 307 cognitive-intact, elder controls were genotyped for ABCA7 rs3764650 and apolipoprotein E (APOE) ε2/ε3/ε4 alleles. Global cognitive performance was...
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