Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel intronic polymorphism of ABCA1 gene reveals risk for sporadic Alzheimer's disease in Chinese.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2007

Chu Leung Wing, Li Yan, Li Zhong, Tang Alan Y B, Cheung Bernard M Y, Leung Raymond Y H, Yik Ping-Yiu, Jin Dong-Yan, Song You-Qiang

Abstract excerpt

Recent genetic studies have shown that variants of the ATP-binding cassette transporter A1, ABCA1, may be implicated in the pathogenesis of Alzheimer's disease (AD). In this case-control study, a panel of 19 single nucleotide polymorphisms (SNP) (including three amino-acid-coding SNPs used for replication of previous work, and 16 newly selected intronic tag SNPs) was genotyped. Nominally significant single marker...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to ATP Binding Cassette Transporter 1

Share to ATP-Binding Cassette Transporters

Share to Introns

Share to Linkage Disequilibrium

Share to Quantitative Trait, Heritable

Source

Identifiers

PMID: 17510949
DOI: 10.1002/ajmg.b.30525

Genes

ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel intronic polymorphism of ABCA1 gene reveals risk for sporadic Alzheimer's disease in Chinese.PMID 17510949Read ↗

An ABCA1 missense variant decreases cholesterol efflux and confers Alzheimer's disease risk in the Chinese population.Semantic proximity Read ↗

ABCA1 rs2230805 and rs2230806 common gene variants are associated with Alzheimer's disease.Semantic proximity Read ↗

A complex association of ABCA7 genotypes with sporadic Alzheimer disease in Chinese Han population.Semantic proximity Read ↗

ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease.Semantic proximity Read ↗

Analyzing large-scale samples confirms the association between the ABCA7 rs3764650 polymorphism and Alzheimer's disease susceptibility.Semantic proximity Read ↗

ATP binding cassette subfamily A member 7 rs3764650 polymorphism and the risk of Alzheimer's disease.Semantic proximity Read ↗

Association between ABCB1 polymorphisms and haplotypes and Alzheimer's disease: a meta-analysis.Semantic proximity Read ↗

Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism.Semantic proximity Read ↗

ABCB1 C3435T polymorphism influences the risk for Alzheimer's disease.Semantic proximity Read ↗

The polymorphism of the ATP-binding cassette transporter 1 gene modulates Alzheimer disease risk in Chinese Han ethnic population.Semantic proximity Read ↗

Quantitative assessment of the effect of ABCA1 gene polymorphism on the risk of Alzheimer's disease.Semantic proximity Read ↗

A survey of ABCA1 sequence variation confirms association with dementia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.