Article
Analyzing large-scale samples confirms the association between the ABCA7 rs3764650 polymorphism and Alzheimer's disease susceptibility.
Molecular neurobiology - 1 Dec 2014
Liu Guiyou, Li Fujun, Zhang Shuyan, Jiang Yongshuai, Ma Guoda, Shang Hong, Liu Jiafeng, Feng Rennan, Zhang Liangcai, Liao Mingzhi, Zhao Bin, Li Keshen
Abstract excerpt
Large-scale genome-wide association studies (GWAS) have revealed that the ABCA7 rs3764650 polymorphism (or its proxies, namely rs115550680, rs3752246, and rs4147929) is associated with Alzheimer's disease (AD) susceptibility in individuals of Caucasian ancestry. The following studies have investigated this finding in Chinese (N = 633 and N = 1,224), Japanese (N = 1,735), Korean (N = 844), African American...
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