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Article

miR-137 targets Myc to regulate growth during eye development.

Development (Cambridge, England) - 15 Jul 2025

Padma Radhika, Subramanian Manivannan, Chimata Anuradha Venkatakrishnan, Rai Arushi, Yogi Sunanda, Sangeeth Anjali, Kango-Singh Madhuri, Singh Amit

Abstract excerpt

During development, regulation of gene expression is key to cellular homeostasis. Gene expression regulation by non-coding RNAs involves the prevention of mRNA accumulation or the inhibition of translation of their target gene. In a forward-genetic screen to identify the microRNA involved in the growth and patterning of the Drosophila eye, we identified the highly conserved miR-137. Gain of function of miR-137...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40554764
DOI: 10.1242/dev.204373
PMCID: PMC12338917

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