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Article

The association of race and ethnicity with risk-reducing mastectomies in patients with non-BRCA mutations.

American journal of surgery - 1 Sept 2025

Ntowe Koumani W, Thomas Samantha M, Dalton Juliet C, Olunuga Ebunoluwa, Wang Ton, Chiba Akiko, Plichta Jennifer K

Abstract excerpt

INTRODUCTION: We compared rates of risk reducing mastectomies (RRM) in patients with breast cancer (BC)-related pathogenic variants. METHODS: Female patients ages ≥18 with a BC-related pathogenic variant, without a concurrent or prior BC diagnosis, were identified from a single academic center's database. Patients were stratified by BRCA mutations, high penetrance mutations (HPM), and moderate penetrance...

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Identifiers

PMID: 40544640
DOI: 10.1016/j.amjsurg.2025.116485
PMCID: PMC12350064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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