Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Demographics and Clinical Decision Making in Patients with Germline Moderate Penetrance Non-BRCA Mutations in Breast Cancer Related Genes.

Annals of surgical oncology - 1 Oct 2024

Ntowe Koumani W, Thomas Samantha M, Dalton Juliet C, Olunuga Ebunoluwa, Wang Ton, Chiba Akiko, Plichta Jennifer K

Abstract excerpt

BACKGROUND: Management of pathogenic variants in high penetrance genes related to breast cancer (BC), such as BRCA1 and BRCA2, are well established. However, moderate penetrance mutations are understudied. We aim to compare risk reduction decision-making patterns in patients with a moderate penetrance BC-related genetic mutations, without a prior BC diagnosis. PATIENTS AND METHODS: Female patients aged ≥ 18 years...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to BRCA1 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA2 Protein

Share to Clinical Decision-Making

Share to Follow-Up Studies

Share to Germ-Line Mutation

Share to Penetrance

Share to Prophylactic Mastectomy

Source

Open in PubMed Open full text

Identifiers

PMID: 38976158
DOI: 10.1245/s10434-024-15793-w
PMCID: PMC11452274

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Demographics and Clinical Decision Making in Patients with Germline Moderate Penetrance Non-BRCA Mutations in Breast Cancer Related Genes.PMID 38976158Read ↗

Risk-reducing mastectomy decisions among women with mutations in high- and moderate- penetrance breast cancer susceptibility genes.Semantic proximity Read ↗

Influential Factors on Risk-reduction Mastectomy in a High-risk Breast Cancer Population With Genetic Predispositions.Semantic proximity Read ↗

Impact of non-BRCA genes in the indication of risk-reducing surgery in hereditary breast and ovarian cancer syndrome (HBOC).Semantic proximity Read ↗

Factors that influence the management recommendations breast surgeons provide to women with pathogenic variants in moderate penetrance breast cancer susceptibility genes.Semantic proximity Read ↗

Pathogenic variants among females with breast cancer and a non-breast cancer reveal opportunities for cancer interception.Semantic proximity Read ↗

Penetrance of Breast Cancer Susceptibility Genes From the eMERGE III Network.Semantic proximity Read ↗

Awareness and Candidacy for Endocrine Prevention and Risk Reducing Mastectomy in Unaffected High-Risk Women Referred for Breast Cancer Risk Assessment.Semantic proximity Read ↗

Timely cancer genetic counseling and testing for young women with breast cancer: impact on surgical decision-making for contralateral risk-reducing mastectomy.Semantic proximity Read ↗

Predicted Chemotherapy Benefit for Breast Cancer Patients With Germline Pathogenic Variants in Cancer Susceptibility Genes.Semantic proximity Read ↗

Assessing, Counseling, and Treating Patients at High Risk for Breast Cancer.Semantic proximity Read ↗

Risk for breast cancer and management of unaffected individuals with non-BRCA hereditary breast cancer.Semantic proximity Read ↗

Timely Cancer Genetic Counseling and Testing for Young Women With Breast Cancer: Impact on Surgical Decision-making for Contralateral Risk-reducing MastectomySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.