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Article

Dissecting the shared genetic architecture of schizophrenia with ventricular subregion volumes.

Cerebral cortex (New York, N.Y. : 1991) - 4 Jun 2025

Zhang Qi, Li Zimeng, Zhao Peng, Liu Xuelai, Jin Zhe-Wu

Abstract excerpt

Schizophrenia is characterized by cerebral ventricular enlargement as an early and consistent structural anomaly. While genetic factors significantly influence both schizophrenia and cerebral ventricular enlargement, the shared genetic etiology between them requires further investigation. Using summary statistics from recent large genome-wide association studies on schizophrenia and 9 ventricular subregion...

Read the complete abstract on PubMed

Topics

Schizophrenia
Humans
Genome-Wide Association Study
Cerebral Ventricles
Genetic Predisposition to Disease
Multifactorial Inheritance

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Phenotype

Polymorphism, Single Nucleotide

Male

Source

Identifiers

PMID: 40474502
DOI: 10.1093/cercor/bhaf132

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