Article

Shared genetic basis for brain structure, insulin resistance and inflammation in schizophrenia: a colocalization study.

2025-09-02

Abstract excerpt

<title>Abstract</title> <p>Psychotic disorders such as schizophrenia (SZ) are associated with structural brain changes and increased cardiometabolic disease risk, potentially linked through shared inflammatory mechanisms. However, whether these associations reflect shared genetic architecture remains unclear. We investigated genetic overlap between SZ, brain structure, insulin resistance (IR), and interleukin (IL...

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Literature Corpus work: e2eb51b3-0eb6-5bf4-8eaa-6b3bab68ea46
DOI: 10.21203/rs.3.rs-7345742/v1

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