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Article

Effect of polygenic risk for schizophrenia on cardiac structure and function: a UK Biobank observational study

8 Jan 2023

Abstract excerpt

Background Cardiovascular disease is a major cause of excess mortality in people with schizophrenia. Several factors are responsible, including lifestyle and metabolic effects of antipsychotics. However, variations in cardiac structure and function are seen in people with schizophrenia in the absence of cardiovascular disease risk factors and after accounting for lifestyle and medication. Therefore, we aimed to...

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PMID: 36632818
DOI: 10.1016/s2215-0366(22)00403-5

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