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Article

Accurate genotyping of three major respiratory bacterial pathogens with ONT R10.4.1 long-read sequencing.

Genome research - 1 Aug 2025

Zidane Nora, Rodrigues Carla, Bouchez Valérie, Rethoret-Pasty Martin, Passet Virginie, Brisse Sylvain, Crestani Chiara

Abstract excerpt

High-throughput massive parallel sequencing has significantly improved bacterial pathogen genomics, diagnostics, and epidemiology. Despite its high accuracy, short-read sequencing struggles with the complete genome reconstruction and assembly of extrachromosomal elements such as plasmids. Long-read sequencing with Oxford Nanopore Technologies (ONT) presents an alternative that offers benefits including real-time...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40456603
DOI: 10.1101/gr.279829.124
PMCID: PMC12315706

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