Article

Performance and Practicality of 16S Nanopore Sequencing for Routine Bacterial Identification in Clinical Samples

2025-12-04

Abstract excerpt

<h4>Background</h4> The accurate and timely identification of bacterial pathogens in low-diversity samples is critical for clinical diagnostics, yet traditional culture-based methods often fail due to prior antibiotic exposure or fastidious growth requirements. While 16S rRNA gene sequencing provides a culture-independent alternative, traditional Sanger sequencing cannot resolve polymicrobial infections, and shor...

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Literature Corpus work: 0aea9d3b-aa70-5ea8-a04e-52c4a11eef0f
DOI: 10.64898/2025.12.04.25341610

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