Article
Closing the gap: Oxford Nanopore Technologies R10 sequencing allows comparable results to Illumina sequencing for SNP-based outbreak investigation of bacterial pathogens.
Journal of clinical microbiology - 8 May 2024
Bogaerts Bert, Van den Bossche An, Verhaegen Bavo, Delbrassinne Laurence, Mattheus Wesley, Nouws Stéphanie, Godfroid Maxime, Hoffman Stefan, Roosens Nancy H C, De Keersmaecker Sigrid C J, Vanneste Kevin
Abstract excerpt
Whole-genome sequencing has become the method of choice for bacterial outbreak investigation, with most clinical and public health laboratories currently routinely using short-read Illumina sequencing. Recently, long-read Oxford Nanopore Technologies (ONT) sequencing has gained prominence and may offer advantages over short-read sequencing, particularly with the recent introduction of the R10 chemistry, which...
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